Author : Naina mohamed pakkir maideen
Keyword : Drug interactions, α-glucosidase inhibitors, acarbose, miglitol, voglibose
Subject : Diabetes
Article Type : Review article
DOI : 10.15406/jdmdc.2019.06.00178
Article File : Full Text PDF
Abstract : The α-glucosidase inhibitors are antidiabetic agents suppressing the postprandial hyperglycemia and they include Acarbose, Miglitol and Voglibose. These drugs could be used alone or as add-on therapy to treat patients with type 2 diabetes taking other antidiabetic drugs. The gastrointestinal motility is increased by the administration of Acarbose, which may lead to decreased absorption of Digoxin and Metronidazole. The glucose lowering effects of antidiabetic drugs such as Metformin, Glibenclamide, Rosiglitazone, Vildagliptin and Dapagliflozin might be enhanced by the coadministration of α-glucosidase inhibitors, though there were reports of little or no alterations in the pharmacokinetics properties of them.
Article by : Naina Mohamed Pakkir Maideen
Article add date : 2021-12-21
How to cite : Naina mohamed pakkir maideen. (2021-December-21). Pharmacologically relevant drug interactions of α-glucosidase inhibitors. retrieved from https://openacessjournal.com/abstract/939